a statistical mechanics perspective Blossey, Ralf creator author. text bibliography flu 2020 Second edition. monographic eng 1 online resource. Computational biology has developed rapidly during the last two decades following the genomic revolution which culminated in the sequencing of the human genome. More than ever it has developed into a field which embraces computational methods from different branches of the exact sciences: pure and applied mathematics, computer science, theoretical physics. This Second Edition provides a solid introduction to the techniques of statistical mechanics for graduate students and researchers in computational biology and biophysics. Material has been reorganized to clarify equilbrium and nonequilibrium aspects of biomolecular systems Content has been expanded, in particular in the treatment of the electrostatic interactions of biomolecules and the application of non-equilibrium statistical mechanics to biomolecules New network-based approaches for the study of proteins are presented. All treated topics are put firmly in the context of the current research literature, allowing the reader to easily follow an individual path into a specific research field. Exercises and Tasks accompany the presentations of the topics with the intention of enabling the readers to test their comprehension of the developed basic concepts. Part 1: Equilibrium statistical mechanics -- Equilbrim statistical mechanics -- Biomolecular structure: DNA, RNA, proteins -- Phase transitions in RNA -- Soft matter electrostatics -- Part 2: Non-equilibrium statistical mechanics -- Back to P: probabilities over time -- Fluctuation theorems -- Dynamics of biological networks -- Biological networks: space. Ralf Blossey. Biomolecules Mechanical properties Statistical mechanics Computational biology SCIENCE / Life Sciences / Biochemistry COMPUTERS / General COMPUTERS / Computer Graphics / Game Programming & Design SCIENCE / Life Sciences / Biology / General QH506 .B57 2020eb 572.80285 9780429503672 0429503679 9780429994616 0429994613 9780429994593 0429994591 9780429994609 0429994605 https://www.taylorfrancis.com/books/9780429503672 http://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf https://www.taylorfrancis.com/books/9780429503672 http://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf OCoLC-P 190614 20260210180715.0 9780429503672 eng