03029cam a2200517Mu 4500 9781351018302 FlBoTFG 20260210180751.0 m d cr cnu---unuuu 190928s2019 flu o 000 0 eng d OCoLC-P eng OCoLC-P 9781351018296 1351018299 9781351018302 (electronic bk.) 1351018302 (electronic bk.) 9781351018289 (electronic bk. : EPUB) 1351018280 (electronic bk. : EPUB) 9781351018272 (electronic bk. : Mobipocket) 1351018272 (electronic bk. : Mobipocket) (OCoLC)1121119891 (OCoLC-P)1121119891 RS431.P37 MED 072000 bisacsh SCI 013000 bisacsh SCI 013050 bisacsh MQP bicssc 615.10285 23 Eswari, J. Satya. Computer-Aided Design of Antimicrobial Lipopeptides As Prospective Drug Candidates [electronic resource]. Boca Raton : CRC Press LLC, 2019. 1 online resource (147 p.) Description based upon print version of record. Increase in antibiotic resistance has forced researchers to develop new drugs against microorganisms. Lipopeptides are produced as secondary metabolites by some microorganisms. Computer-aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates provides the identification of novel ligands for different antimicrobial lipopeptides. Along with identification, it also provides some of the in silico drug design processes, namely homology modelling, molecular docking, QSAR studies, drug ADMET studies and pharmacophore studies to check the ligand-lipopeptide interaction. Some lipopeptides have shown anti-cancerous properties too, and this book discusses the required templates to design new drugs using computational techniques. Key Features: Focuses on the use lipopeptides as new antimicrobial compounds Presents the basics of in silico modelling for design and development of new drug molecules, and is therefore of interest to beginners in the field Provides a step-by-step process for identification of drug molecules and testing its efficacy in silico Couples with courses on patents and intellectual property rights OCLC-licensed vendor bibliographic record. MEDICAL / Pharmacy bisacsh SCIENCE / Chemistry / General bisacsh SCIENCE / Chemistry / Physical & Theoretical bisacsh Peptide antibiotics Design. Drugs Computer-aided design. Drug development Computer-aided design. Dhagat, Swasti. Yadav, Manisha. Taylor & Francis https://www.taylorfrancis.com/books/9781351018302 OCLC metadata license agreement http://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf 90623 90622